The Relationship Between Endometrial Biopsy Results and Covid-19 in Postmenopausal Women

INTRODUCTION: To investigate the impact of Covid-19 infection on postmenopausal bleeding and endometrial sampling results in postmenopausal women.
METHODS: Our study is a retrospective study, and it compares the demographic data, transvaginal ultrasound findings, and histopathological results of endometrial biopsies in postmenopausal women who had postmenopausal bleeding or underwent endometrial sampling due to asymptomatic endometrial thickness increase of the groups of those who had and had not experienced Covid-19 at Ankara City Hospital between October and December 2020.
RESULTS: Among the 274 patients included in our study, it was observed that biopsies were taken from 173 (63.13%) due to postmenopausal bleeding (PMB), and from 101 (31.86%) asymptomatic women due to increased endometrial thickness. It was determined that 60 (21.89%) of the women had experienced Covid-19 infection. The mean endometrial thickness in patients who underwent biopsy was 8.93±6.42mm, and no significant difference was observed between the measured endometrial thickness in the groups who had and had not experienced Covid-19 (7.98±4.80 vs 9.20±6.79; p=0.17). It was observed that 37 of the 173 patients (21.39%) who had samples taken due to PMB had experienced Covid-19. In both groups of patients who had and had not experienced Covid-19, no significant difference was observed in the rates of postmenopausal bleeding and in the benign and malignant pathology results from the histopathological examination (p > 0.05).
DISCUSSION AND CONCLUSION: In terms of our study in postmenopausal women, it was observed that Covid-19 infection did not affect the rates of postmenopausal bleeding and endometrial biopsy results.