ISSN :2822-5872
Pineal gland germinoma and pituitary insufficiency presenting with weight loss: Rare Case [ACH Medical Journal]
ACH Medical Journal. 2023; 2(1): 32-35 | DOI: 10.5505/achmedj.2023.76486

Pineal gland germinoma and pituitary insufficiency presenting with weight loss: Rare Case

Emine Sena Sözen, Oguzhan Zengin, Enes Seyda Şahiner
Department of Internal Medicine,Ankara Bilkent City Hospital,Ankara,Turkey

Intracranial germinomas are rare cancers that primarily affect pediatric age group patients making them rarer still in adults.
This report presents a case of a primary intracranial germinoma arising in the pineal region of a 24 year old male. The patient presented with a history of weight loss and progressive vision loss secondary to obstructive hydrocephalus. MRI demonstrated a large enhancing mass lesion in the region of the pineal gland with radiological features suggestive of a germinoma.
Immunohistochemical stains confirmed the histological diagnosis, with positive staining for C-Kit, OCT4 and PLAP.
In summary, this case report highlights that the diagnosis of pineal gland germinoma present in a young male is made by immunohistochemistry and detailed physical examination.

Keywords: Pineal Germinoma, Weight Loss, Pituitary Insufficiency

Emine Sena Sözen, Oguzhan Zengin, Enes Seyda Şahiner. Pineal gland germinoma and pituitary insufficiency presenting with weight loss: Rare Case. ACH Medical Journal. 2023; 2(1): 32-35

Corresponding Author: Emine Sena Sözen, Türkiye
Manuscript Language: English