ISSN :2822-5872
ANKARA CITY HOSPITAL MEDICAL JOURNAL - ACH Medical Journal: 3 (3)
Volume: 3  Issue: 3 - September 2024
1.Full Issue

Pages I - II

RESEARCH ARTICLE
2.Does Removal Of Volar Locking Plate Affect Patient Functional Outcomes?
Enver Kılıç, Mehmet Fatih Savaş
doi: 10.5505/achmedj.2024.73745  Pages 90 - 95
INTRODUCTION: The aim of our study is to evaluate the effect of volar locking plate (VLP) removal on functional scores.
METHODS: In this retrospective study, between January 2019 and January 2024, medical records of our institution were reviewed and patients who underwent VLP removal were included in the study. Demographic characteristics of the patients, follow-up time until VLP removal and reasons of VLP removal were evaluated from medical records. Preoperative and postoperative 3rd month Disabilities of Arm, Shoulder and Hand (DASH) scores were evaluated. Soong classification was performed on lateral wrist radiographs.
RESULTS: Thirty-eight patients (24 male, 14 female) patients were included in the study. The mean age of all patients was 51.23±15.6 years. The mean time from VLP fixation to implant removal was 17.42±12.42 months. Patients who underwent implant removal were evaluated according to the Soong classification. 18 of the patients (%47.36) were grade 0, 16 of the patients (%42.1) were grade 1 and 4 of the patients (%10.54) were grade 2. The most common removal reason was patient request (n=26, %68.42). Preoperative mean DASH score was 19.1 and postoperative 3rd month mean DASH score was 8.2. There was a significant difference between preoperative and postoperative 3rd month DASH scores. (p<0.001) When patients were asked whether they would choose to implant removed again if they were in the same situation, %94.7 of the patients stated that they would choose implant removal again.
DISCUSSION AND CONCLUSION: VLP removal provided significant improvement in the patients' functional outcomes. The most common reason for VLP removal was patient request.

3.Scar Endometriosis After Cesarean Section; Our Clinical Experiences, 32 Cases of Cesarean Scar Endometriosis
İnci Halilzade, Elcin Islek Secen, Gonca Türker Ergün, Ayse Filiz Yavuz
doi: 10.5505/achmedj.2024.87587  Pages 96 - 101
INTRODUCTION: Scar endometriosis is a type of rare endometriosis that develops following obstetric or gynecological surgeries. The aim of our study is to share our clinical experiences regarding scar endometriosis, which is becoming more common due to increasing cesarean operations, and to contribute to the literature on this subject.
METHODS: A total of 32 patients who underwent surgery due to scar endometriosis participated in our study. The patients' demographic and clinical characteristics, size and location of the lesion determined by imaging methods and histopathological results were recorded and analyzed.
RESULTS: The mean age of the patients was 34.81±6.52 years, with 46.9% having undergone one cesarean section and 53.1% having undergone two or more cesarean sections. Scar endometriosis involving subcutaneous and fascial tissue was determined to be 43.7% in the right corner, 28.1% in the left corner, 9.4% in the midline, and 18.8% within the rectus muscle. The time elapsed between cesarean section and the onset of symptoms was found to be statistically significantly shorter in patients who had undergone two or more cesarean sections compared to those with only one previous cesarean section (p=0.015).
DISCUSSION AND CONCLUSION: Scar endometriosis is a painful condition for which clear success in medical treatment has not yet been demonstrated, and surgical intervention is often required. Given the higher frequency of occurrence at the corners of cesarean section incisions, we recommend the careful washing of these corners. Further immunohistochemical studies are needed to achieve success in medical treatment, and histopathological analysis should be fully elucidated.

4.Effects of cesarean section duration on inflammation and postoperative parameters, a retrospective analysis
Şükrü Bakırcı, Hilal Gözüyukarı, Sabri Kurtay, Ayşe Gizem Saraçoğlu, Banu Yüce
doi: 10.5505/achmedj.2024.70299  Pages 102 - 106
INTRODUCTION: Cesarean section it is the most frequently applied surgical application. Every surgical procedure creates an inflammation. Neutrophil to lymphocyte ratio (NLR), which can be easily obtained from complete blood count, is used as subclinical systemic inflammatory markers. In this study, our aim is to understand the effect of the duration of the cesarean section on subclinical inflammation by looking at the neutrophil/lymphocyte ratio and the effect of this period on blood loss and postoperative recovery
METHODS: We included a total of 188 operations between the ages of 18-45 in our study and created 2 groups according to the duration of the cesarean section. When grouped as short (0-39 min) and long (≥40 min) according to the operation time, NOL change was higher in the group with longer operation duration, but no significant difference was found in both groups. Similarly, although the decrease in hemoglobin was higher in the group with a long operation time, no significant difference was found. No difference was observed between the two groups in terms of wound healing on the postoperative 10th day. When we look at our other parameters, we found a significant relationship between those whose cesarean section ended within 40 minutes and those who had their first cesarean section.
RESULTS: As a result of our study, we could not detect a significant difference in the duration of the cesarean section operations performed in our clinic on the postoperative parameters.
DISCUSSION AND CONCLUSION: Although supportive studies are needed, it shows that the surgical rules of cesarean section operate correctly under optimal conditions.

5.Prenatal diagnosis and postnatal outcomes of cavum septum pellucidum et vergae
Hakkı Şerbetçi, Atakan Tanacan, Refaettin Sahin, Osman Onur Özkavak, Murat Haksever, Mehmet Utku Başarır, Özgür Kara, Dilek Şahin
doi: 10.5505/achmedj.2024.43534  Pages 107 - 111
INTRODUCTION: Evaluation of demographic characteristics and postnatal outcomes of fetuses with cavum septum pellucidum et vergae (CSPV) diagnosis followed in a tertiary center.
METHODS: This retrospective study was conducted in Ankara Bilkent City Hospital perinatology clinic between 2020-2023. Cases with the prenatal diagnosis of CSPV were evaluated. Demographic features, prenatal ultrasound findings, noninvasive screening test results, invasive diagnostic test results, prenatal anomaly screening ultrasound findings, and postnatal outcomes were reported.
RESULTS: There was a total of 24 prenatally diagnosed CSPV cases during the study period. The mean gestational week at diagnosis was 25.6 ± 3.2 weeks. Nineteen patients participated in noninvasive screening tests; five patients declined them. Noninvasive screening tests revealed low risk in 17 patients and high risk in 2. Amniocentesis was performed in 5 patients; 3 of them had a normal karyotype, 1 fetus was diagnosed with Smith-Lemli-Opitz syndrome, and 1 fetus had trisomy 21. Six patients with isolated CSPV were accepted and underwent fetal MRI, other eighteen patients refused MRI. MRI corrected the CSPV in all six patients, and they had no additional findings. Five (%21) fetuses were admitted to the intensive care unit because of recurrent absence convulsions (n=1), anal atresia (n=1), cleft lip palate (n=1), respiratory distress (n=1) and hypoplastic left heart syndrome (n=1).
DISCUSSION AND CONCLUSION: CSPV is considered a normal variant of cavum septum pellucidum and can be diagnosed during ultrasound screening for fetal anomalies; in isolated cases perinatal outcomes are favorable.

6.Effect of specific immunotherapy on plasma interleukin 13 and 8 levels in patients with allergic rhinitis
Gülşen Duman Talas, Göksal Keskin
doi: 10.5505/achmedj.2024.03016  Pages 112 - 117
INTRODUCTION: This study aimed to evaluate interleukin (IL)-13 and IL-8 levels in patients with allergic rhinitis who were and were not receiving specific immunotherapy.

METHODS: A total of 84 patients being followed up in the immunology-allergy outpatient clinic for allergic rhinitis (42 receiving immunotherapy) and 23 healthy control subjects were included. Serum IL-13 and IL-8 levels were measured by enzyme-linked immunosorbent assay in all groups. Allergic rhinitis patients were also evaluated in terms of symptom scores, IgE levels, and skin prick test results.

RESULTS: Comparison of serum IL-13 and IL-8 among the groups demonstrated that levels of both cytokines were significantly higher in both allergic rhinitis patient groups compared to controls (p<0.001), and significantly higher in symptomatic allergic rhinitis patients compared to patients receiving immunotherapy (p<0.001 for IL-13, p=0.004 for IL-8).

DISCUSSION AND CONCLUSION: Immunotherapy is the only curative treatment for allergic rhinitis. The results of our study suggest that immunotherapy exerts its effect by modifying levels of IL-13 and IL-8 in addition to previously well-known cytokines.


CASE REPORT
7.Navigating Rhupus Complexity
Dilara Bulut Gökten, Ridvan Mercan
doi: 10.5505/achmedj.2024.95967  Pages 118 - 122
The term 'Rhupus,' introduced by Peter Schur in 1971, describes patients meeting criteria for both rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Rhupus (RhS) is a rare syndrome, and approximately 60 cases have been described in the literature to date. The challenges in diagnosing this disease stem from the lack of well-defined clinical criteria. In this case, we present a 42-year-old female patient with overlap syndrome of RA and SLE (RhS) who developed inflammatory arthritis, swelling in her bilateral wrists, severe malar rash, oral ulcers and alopecia, anemia and thrombocytopenia during follow-up. Upon arrival, the patient’s laboratory values were as follows: erythrocyte sedimentation rate: 61 mm/hour (normal value: 0-20), hemoglobin: 8.3 g/dL (12-16), platelet count: 112.103/µL (150-450.103/µL). The purpose of documenting this case is to share our own experience with a syndrome that is quite rare and has the potential to cause confusion in the daily practice of clinicians.